Amphipathic Molecule

As it pertains to the biological systems, explain what is meant by “dynamic steady state.” Provide examplesExplain what is meant by the term an “amphipathic” molecule. Provide examplesExplain what sets the lower limit of the cell size and the upper limit.The antidepressant medication citalopram (trade name Celexa), a selective serotonin reuptake inhibitor, is a racemic mixture of the two isomers, but only (S)-citalopram has the therapeutic effect. A stereochemically pure preparation of (S)-citalopram (escitalopram oxalate) is sold under the trend name Lexapro.Explain what is meant by “stereospecificityExplain why ionic attractions are weaker in media with high dielectric constants, e. g., water and aqueous buffers.Explain how cellular communication occurs on molecular and cellular levels. Provide examples.In regards to the protein structure, explain what is meant by “quaternary structure.” What are the main forces that stabilize quaternary structures in proteins? Provide examples.In your understanding, do you think that the following statement is correct: “Water is an effective solvent for living systems because of its inert behavior”? Why or why not? Explain your answer.Explain Endosymbiotic Theory; provide supporting evidence that substantiates this theory.Explain why hydrophobic molecules aggregate together when placed in water and aqueous buffers. What is the thermodynamic driving force for this separation?Amino acid thyroxine is an iodine containing biological derivative of tyrosine and is a major hormone, T4, secreted by the follicular cells of the thyroid gland. The three pKa values for thyroxine are pK1 = 2.2, pK2 = 10.1, and pKR = 6.5 (see structure below). Would it be correct to say that at physiological pH 7.4, [Fully deprotonated thyroxine] > [Fully ionized thyroxine]? Explain your answer.Explain why those biological reactions that have their equilibria shifted towards the products have negative values for ΔGo of reactions. Explain how equilibria relates to Gibbs free energy.Explain why synthesis of a dipeptide from two individual amino acids is energetically unfavorable. Explainhow this unfavorable synthesis occurs in biological systems.The mitochondrial enzyme fumarase is involved in the Krebs Cycle, and catalyzes the reversible hydration of fumarate to (S)-malate. What is the ΔGo′ (in kJ/mol) for the forward reaction catalyzed by mitochondrial fumarase at an average adult body temperature of 37 oC? Equilibrium concentrations of the reactants and products are given below for each of the components. You must show your calculations.Normally, in mammals the body maintains the blood glucose level at a reference range between 3.6 and 5.8 mM (mmol/L). It is tightly regulated as a part of metabolic homeostasis. Explain what would happen if red blood cells were placed into a solution containing 0.5 mM glucose; what would be the term that describes this solution?The pH of blood in normal individuals is 7.4, while alcohol abuse may result in blood pH elevated to as high as 8.0, a condition known as metabolic alkalosis. Calculate the ratio of hydronium ions in blood of a normal individual to that of a person with alcohol abuse. You must show your calculations.MOPS (3-(N-morpholino) propanesulfonic acid) is a physiologically relevant acid has a pKa of 7.2. What would be pH of the buffer prepared from equal amounts of 15 mM MOPS acid and 6 mM MOPS base? Show your calculations. Would this prepared buffer be a suitable buffer? Explain your answer.Calculate the molar extinction coefficient of tryptophan (in M‒1cm‒1) (MW 204.23 g/mol) if 0.01 g sample is prepared in 100 mL buffer, the above solution produced an absorbance of 2.74 when using a spectrophotometer with a cuvette path length of l = 1 cm.Calculate the net charge on the following nonapeptide at the physiological pH 7.4, and predict the peptide’s mobility in an electric field.Explain your answer.Tyr – Ala – Phe – Lys – Gly – Cys – Ser – His – AspExplain how the directionality of bonding may affect the strength of the hydrogen bondsA mixture of urease (pI = 5.1; MW 482,000), catalase (pI =5.6; MW 247,500), lactoglobulin (pI = 5.2; MW 37,100) and hemoglobin (pI = 6.9; MW 64,500) were applied in a pH 6.5 buffer to a CM-cellulose (cation exchanger resin) chromatography column and eluted with the same buffer. What is their order of elution? How would you elute bound proteins from this type of resin? Explain your answer.Explain the theory behind gel filtration chromatography.In a mixture of five proteins listed, draw an elution profile (Absorbance vs. mL eluted, arbitrary) for the purification of the listed proteins on a gel filtration chromatography resin: Cytochrome c (Mr = 13,000), Immunoglobulin G (Mr = 145,000), Ribonuclease A (Mr = 13,700), RNA polymerase (Mr = 450,000), Serum albumin (Mr = 68,500). Label your elution peaks.Draw a sketch of an SDS-PAGE, reflecting the mobility of the above mixture as they elute from the column. Label you protein bands.A peptide was found to have a molecular mass of about 550 and upon hydrolysis produced Ala, Asp, Cys, Lys and Phe in a 1:1:1:1:1 ration. The peptide upon treatment with Sanger’s reagent (FDNB) produced DNP-Cys and upon exposure to carboxypeptidase produced aspartate residue. Chymotrypsin treatment of the above peptide produced a dipeptide that contained sulfur and had a UV absorbance, and a tripeptide. Exposure of the original peptide to trypsin produced a dipeptide and a tripeptide. Deduce the sequence of the peptide analyzed. Explain in detail the rationale behind your answer.

Calculate the price
Make an order in advance and get the best price
Pages (550 words)
*Price with a welcome 15% discount applied.
Pro tip: If you want to save more money and pay the lowest price, you need to set a more extended deadline.
We know how difficult it is to be a student these days. That's why our prices are one of the most affordable on the market, and there are no hidden fees.

Instead, we offer bonuses, discounts, and free services to make your experience outstanding.
How it works
Receive a 100% original paper that will pass Turnitin from a top essay writing service
step 1
Upload your instructions
Fill out the order form and provide paper details. You can even attach screenshots or add additional instructions later. If something is not clear or missing, the writer will contact you for clarification.
Pro service tips
How to get the most out of your experience with Assignments ABC
One writer throughout the entire course
If you like the writer, you can hire them again. Just copy & paste their ID on the order form ("Preferred Writer's ID" field). This way, your vocabulary will be uniform, and the writer will be aware of your needs.
The same paper from different writers
You can order essay or any other work from two different writers to choose the best one or give another version to a friend. This can be done through the add-on "Same paper from another writer."
Copy of sources used by the writer
Our college essay writers work with ScienceDirect and other databases. They can send you articles or materials used in PDF or through screenshots. Just tick the "Copy of sources" field on the order form.
See why 10k+ students have chosen us as their sole writing assistance provider
Check out the latest reviews and opinions submitted by real customers worldwide and make an informed decision.
Thank you so much! I appreciate what you do and all of the great help you've given me!
Customer 452483, September 6th, 2021
Good job! Thank you.
Customer 452487, October 26th, 2021
English 101
Perfect! Very informative! Appreciate all of your hard work! Thank you very much.
Customer 452483, September 22nd, 2021
Very clear, and complete information presented. I, thank you for all of your hard work, appreciate it!
Customer 452483, August 9th, 2021
English 101
Perfect! Thank you so much for all of your hard work and help! Appreciate it!!
Customer 452483, August 30th, 2021
Healthcare Writing & Communications
Excellent!! You’re awesome, thank you very much for all of your hard work & help!!
Customer 452483, October 24th, 2021
I appreciate the help.
Customer 452567, March 18th, 2022
Introduction to Sociology
Amazing! Thank you so much for your hard work, appreciate it!!
Customer 452483, October 24th, 2021
thank you
Customer 452639, January 24th, 2023
Well done! I thank you very much!
Customer 452483, July 9th, 2021
Classic English Literature
Great paper, thank you!
Customer 452591, May 5th, 2022
Appreciate all of your hard work! Thank you so much!!
Customer 452483, September 14th, 2021
Customer reviews in total
Current satisfaction rate
2 pages
Average paper length
Customers referred by a friend
15% OFF your first order
Use a coupon ABC15 and enjoy expert help with any task at the most affordable price.
Claim my 15% OFF Order in Chat